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Structure of 773134-90-0
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Ethyl 2,3,6-trifluorobenzoate features a trifluorinated aromatic core that imparts enhanced electron-withdrawing character and metabolic stability. This structural motif enables efficient incorporation into complex synthetic intermediates, particularly in pharmaceutical and agrochemical scaffold development. The ester functionality offers straightforward derivatization potential under standard conditions.
Ethyl 2,3,6-trifluorobenzoate serves as a versatile trifluorinated aromatic building block for medicinal chemistry and materials synthesis. Its electron-deficient benzene ring facilitates nucleophilic aromatic substitution, while the ester group enables further functionalization via hydrolysis or coupling reactions. The ortho-fluorine atoms provide enhanced metabolic stability and improved binding affinity in bioactive scaffolds. Bench-stable and compatible with standard reaction conditions, it functions reliably in cross-coupling, acylation, and heterocycle formation workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: