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Structure of 77324-87-9
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Methyl 5-nitro-2-methylbenzoate is a bench-stable, electron-deficient aromatic ester featuring a para-nitro group and ortho-methyl substituent. This combination enhances reactivity in electrophilic substitution and provides structural rigidity for use in synthetic intermediates. The methyl ester moiety enables straightforward derivatization under standard conditions.
Methyl 5-nitro-2-methylbenzoate serves as a versatile synthetic intermediate in heterocyclic chemistry and medicinal compound development. Its ortho-methyl and meta-nitro substituents enable selective functionalization, including directed metalation and catalytic cross-coupling reactions. The ester group facilitates derivatization, while the nitro moiety provides strong electron-withdrawing character for subsequent reduction or nucleophilic substitution. Bench-stable and readily purified by recrystallization, it functions as a reliable building block in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: