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Structure of 77395-10-9
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5-Bromo-7-methylindoline-2,3-dione features a brominated indoline core with a methyl substituent at the 7-position, delivering enhanced electron-withdrawing character and improved solubility in polar organic solvents. This scaffold integrates readily into synthetic intermediates for pharmaceuticals and agrochemicals, offering high stability under standard handling conditions and compatibility with transition-metal-catalyzed couplings.
5-Bromo-7-methylindoline-2,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indole and isoindolinone scaffolds. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, while the electron-deficient dione framework supports nucleophilic additions and cycloadditions. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: