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Structure of 774-47-0
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5,6-Difluoroindoline-2,3-dione features a highly electron-deficient fused ring system with fluorine substituents at the 5 and 6 positions, enhancing its reactivity in cycloaddition and coupling processes. This bench-stable, moisture-tolerant heterocycle integrates readily into complex molecular architectures, offering precise control over regiochemistry and electronic properties in synthetic applications.
5,6-Difluoroindoline-2,3-dione serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds through standard cycloaddition and electrophilic substitution reactions. Its electron-deficient core facilitates efficient coupling with nucleophiles, while the difluoro substitution enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: