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CS-W001157 4
Total: USD 88.00

2-(3-Bromo-4-methoxyphenyl)acetic acid

  • CAS No. 774-81-2

  • Cat. No. CS-0037013
  • Purity≥98%
  • MDL No.MFCD00017538

*For research and further manufacturing use only, not for direct human use.

2-(3-Bromo-4-methoxyphenyl)acetic acid|CS-0037013

Structure of 774-81-2

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General Information

  • CAS No. 774-81-2
  • Cat. No. CS-0037013
  • Purity ≥98%
  • MDL No. MFCD00017538
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BrO₃
  • Molecular Weight 245.07
  • Synonym(s) Benzeneacetic acid,3- bromo-4-methoxy-
  • SMILES COC1=C(C=C(C=C1)CC(=O)O)Br

Description

This brominated phenylacetic acid derivative features a methoxy-substituted aromatic ring, enabling selective functionalization in synthetic pathways. The para-methoxy group enhances electron density, while the ortho-bromo substituent provides a handle for cross-coupling reactions. Bench-stable and compatible with standard reaction conditions, it serves as a key intermediate in medicinal chemistry and materials synthesis.

Application

2-(3-Bromo-4-methoxyphenyl)acetic acid serves as a versatile building block for pharmaceutical intermediates, enabling palladium-catalyzed cross-coupling reactions due to its bromoaryl functionality. The methoxy group enhances solubility and modulates electronic properties, while the carboxylic acid facilitates derivatization and purification. Bench-stable and compatible with standard synthetic workflows, it functions effectively in the construction of bioactive heterocycles and API scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H319-H410
Precautionary Statements : P264-P273-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364-P391-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.0848
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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