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Structure of 775351-54-7
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2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile features a boronate ester group paired with a nitrile and methyl substituent on an aromatic ring. This configuration enables stable coupling in Suzuki-Miyaura reactions under standard conditions, delivering arylated products with high fidelity. The tetramethylcyclopentadienyl boronate moiety enhances shelf stability and moisture tolerance during handling.
2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The nitrile group enables further functionalization, while the tetramethyl-substituted dioxaborolane offers enhanced stability and reactivity under standard conditions. This compound facilitates efficient C–C bond formation with aryl halides and pseudohalides, making it valuable for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: