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CS-W001157 4
Total: USD 88.00

1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide

  • CAS No. 77542-18-8

  • Cat. No. CS-0029582
  • Purity≥95%
  • MDL No.MFCD16620306
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide|CS-0029582

Structure of 77542-18-8

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Description

1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide is a stable, bench-ready quaternary ammonium salt featuring a cyclic amine core with enhanced solubility in polar solvents. The piperidinium cation bears both ethyl and methyl substituents that modulate electronic distribution and steric profile. This structure facilitates efficient alkylation reactions and serves as a robust synthetic intermediate in medicinal chemistry.

Application

1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide serves as a versatile quaternary ammonium salt that functions as a stable, bench-ready electrophile in nucleophilic substitution reactions. Its cyclic structure provides enhanced rigidity and predictable reactivity, enabling efficient C–N bond formation under mild conditions. The compound exhibits good solubility in polar solvents and tolerance to common functional groups, facilitating its use in the synthesis of complex heterocycles and pharmaceutical intermediates.

General Information

  • CAS No. 77542-18-8
  • Cat. No. CS-0029582
  • Purity ≥95%
  • MDL No. MFCD16620306
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆INO
  • Molecular Weight 269.12
  • Synonym(s) N-Ethyl-N-methyl-4-piperidonium iodide; N-Methyl-N-ethyl-4-oxopiperidinium iodide; PiperidiniuM, 1-ethyl-1-Methyl-4-oxo-, iodide (1
  • SMILES O=C1CC[N+](C)(CC)CC1.[I-]

Computational Chemistry Data

  • TPSA   17.07
  • LogP   -2.1802
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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