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Structure of 77924-28-8
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4-tert-Butyl 1-ethyl 2-(diethoxyphosphoryl)succinate features a sterically hindered tert-butyl group and a diethoxyphosphoryl moiety, enabling robust participation in asymmetric synthesis. This bench-stable phosphonate ester integrates readily into Michael additions and Horner-Wadsworth-Emmons reactions, delivering high stereoselectivity with minimal side-product formation under standard conditions.
4-tert-Butyl 1-ethyl 2-(diethoxyphosphoryl)succinate serves as a versatile synthon in the synthesis of phosphorylated heterocycles and bioactive molecules. Its diester functionality enables efficient Michael additions, aldol condensations, and Pudovik reactions, while the tert-butyl group provides steric protection and enhanced bench stability. The molecule functions effectively in standard enolate chemistry and facilitates the construction of phosphonate-containing scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: