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CS-W001157 4
Total: USD 88.00

1-(9H-Fluoren-2-yl)ethanone

  • CAS No. 781-73-7

  • Cat. No. CS-W015210
  • Purity≥95%
  • MDL No.MFCD00001124

*For research and further manufacturing use only, not for direct human use.

1-(9H-Fluoren-2-yl)ethanone|CS-W015210

Structure of 781-73-7

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General Information

  • CAS No. 781-73-7
  • Cat. No. CS-W015210
  • Purity ≥95%
  • MDL No. MFCD00001124
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₂O
  • Molecular Weight 208.26
  • Synonym(s) 2-Acetylfluorene
  • SMILES CC(C1=CC(CC2=C3C=CC=C2)=C3C=C1)=O

Description

1-(9H-Fluoren-2-yl)ethanone features a fluorenone core with a reactive ketone at the 2-position, enabling direct functionalization in synthesis. This bench-stable, moisture-tolerant reagent integrates readily into C–C bond-forming reactions and serves as a key intermediate in constructing polycyclic architectures.

Application

1-(9H-Fluoren-2-yl)ethanone serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of fluorene-based scaffolds. Its ketone functionality facilitates nucleophilic additions, reductions, and electrophilic substitutions, while the rigid fluorene core enhances structural stability. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for applications in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Kovalev, Aleksei I.; Shapovalov, Aleksei V.; Sukhorukova, Evgeniya V.; Sergeev, Alexander M.; Peregudov, Alexander S.; Rusanov, Alexander L.; Khotina, Irina A. Mendeleev Communications, 2011 , vol. 21, # 1 p. 9 - 11
  • Route2
    • In-stock
      Fluorene|CS-0070796
      86-73-7
    • null|null
      108-24-7
    • ~56%
    • In-stock
      1-(9H-Fluoren-2-yl)ethanone|CS-W015210
      781-73-7

    References

    • Zhang, Qin; Jiang, Peng; Wang, Kunyan; Song, Guangliang; Zhu, Hongjun Dyes and Pigments, 2011 , vol. 91, # 1 p. 89 - 97
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 83, p. 4825 - 4829

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.4604
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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