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CS-W001157 4
Total: USD 88.00

(S)-2-Hydroxy-2,3-dimethylbutanoic acid

  • CAS No. 78640-99-0

  • Cat. No. CS-0460186
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-Hydroxy-2,3-dimethylbutanoic acid|CS-0460186

Structure of 78640-99-0

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General Information

  • CAS No. 78640-99-0
  • Cat. No. CS-0460186
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₃
  • Molecular Weight 132.16
  • Synonym(s) (2S)-2-Hydroxy-2,3-dimethylbutanoic acid
  • SMILES CC(C)[C@](C)(O)C(O)=O

Synthesis

  • Route1
    • null|null
      1155842-22-0
    • ~50%
    • (S)-2-Hydroxy-2,3-dimethylbutanoic acid|CS-0460186
      78640-99-0

    References

    • AMGEN INC.; CAILLE, Seb; CUI, Sheng; WANG, Silas; FAUL, Margaret Patent: WO2010/14586 A1, 2010 ; Location in patent: Page/Page column 24 ; WO 2010/014586 A1
  • Route2
    • null|null
      78641-06-2
    • ~38%
    • (S)-2-Hydroxy-2,3-dimethylbutanoic acid|CS-0460186
      78640-99-0

    References

    • Wetter, Hansjuerg Helvetica Chimica Acta, 1981 , vol. 64, # 3 p. 761 - 768
  • Route3
    • null|null
      563-80-4
    • null|null
      74-90-8
    • ~%
    • (R)-2-Hydroxy-2,3-dimethylbutanoic acid|CS-1360124
      92735-50-7
    • (S)-2-Hydroxy-2,3-dimethylbutanoic acid|CS-0460186
      78640-99-0

    References

    • Effenberger; Horsch; Weingart; Ziegler; Kuhner Tetrahedron Letters, 1991 , vol. 32, # 23 p. 2605 - 2608

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.478
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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