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Structure of 78756-37-3
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Ethyl 8-bromo-5-methyl-6-oxo-5,6-dihydro-4h-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate features a sterically hindered brominated heterocyclic core with a bench-stable oxo group and a methyl-substituted imidazodiazepine scaffold. This electron-deficient system integrates readily into complex scaffolds for medicinal chemistry campaigns requiring halogenation handles and rigidified ring systems.
Ethyl 8-bromo-5-methyl-6-oxo-5,6-dihydro-4h-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate serves as a versatile building block for the synthesis of fused heterocyclic scaffolds. Its bromo and ester functionalities enable palladium-catalyzed cross-coupling and hydrolysis reactions, respectively, while the 6-oxo group supports enolization and nucleophilic addition. The molecule exhibits bench stability and facilitates efficient purification, making it suitable for iterative medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: