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Structure of 78851-85-1
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This sulfamoyl-thiadiazole conjugate features a strategically positioned oxo group and carboxylic acid functionality, enabling direct integration into bioconjugation workflows. The electron-deficient thiadiazole ring enhances stability under physiological conditions while the sulfamoyl moiety improves solubility in aqueous systems.
4-Oxo-4-((5-sulfamoyl-1,3,4-thiadiazol-2-yl)amino)butanoic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to sulfonamide-containing scaffolds. Its amide-linked thiadiazole moiety offers enhanced metabolic stability and hydrogen-bonding capacity, while the β-ketoacid functionality facilitates cyclization and derivatization under mild conditions. The compound exhibits good bench stability and compatibility with standard purification methods, making it suitable for medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: