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Structure of 789-61-7
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Intercalating into telomeric DNA repeats, 6-Thio-2′-Deoxyguanosine (CAS 789-61-7) induces replication stress and triggers senescence in proliferating cell lines through aberrant telomere elongation.
6-Thio-2′-Deoxyguanosine (CAS 789-61-7) enables real-time monitoring of secreted luciferase activity in tonsillar cancer cells by integrating into DNA and triggering detectable luminescence upon metabolic activation. This allows precise tracking of tumor cell proliferation. Researchers exploit this feature to evaluate drug efficacy in live-cell assays.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: