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Structure of 79055-52-0
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2,4-Dibromo-6-methylpyridine features a pyridine core substituted with bromine atoms at the 2 and 4 positions and a methyl group at the 6 position, creating a sterically hindered, electron-deficient heterocycle. This configuration enables direct coupling in palladium-catalyzed cross-coupling reactions, offering efficient access to functionalized pyridine scaffolds under standard conditions.
2,4-Dibromo-6-methylpyridine serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal bromine reactivity. The methyl group enhances regioselectivity in electrophilic substitutions, while the pyridine core provides strong coordination for transition metals. Bench-stable and amenable to purification via recrystallization, it facilitates efficient synthesis of complex heterocyclic scaffolds and functionalized aryl derivatives in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: