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Structure of 79477-87-5
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2-(3-Fluorophenyl)-2-oxoacetic acid features a fluorinated aromatic ring conjugated to a reactive ketonic acetyl moiety, enabling direct integration into heterocyclic syntheses. This bench-stable, moisture-tolerant reagent facilitates efficient access to functionalized pyrazoles and oxazoles under mild conditions.
2-(3-Fluorophenyl)-2-oxoacetic acid serves as a versatile building block for heterocyclic synthesis, particularly in the construction of quinoline and isoquinoline scaffolds. Its α-keto acid functionality enables efficient condensation reactions with amines and hydrazines, facilitating rapid access to bioactive nitrogen-containing frameworks. The 3-fluorophenyl group enhances metabolic stability and modulates electronic properties, improving target affinity in medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: