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Structure of 79669-49-1
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5-Bromo-2-methylbenzoic acid is a sterically hindered, electron-deficient aromatic carboxylic acid featuring a bromine atom at the meta position relative to the carboxyl group and a methyl substituent ortho to the carboxyl. This combination enhances regioselectivity in coupling reactions and improves stability under standard bench conditions. The molecule integrates readily into pharmaceutical intermediates and functional materials via amide formation or metal-catalyzed cross-coupling.
5-Bromo-2-methylbenzoic acid serves as a versatile building block for the synthesis of functionalized aromatic scaffolds, enabling direct coupling reactions via its carboxylic acid group. The bromo and methyl substituents provide orthogonal handles for palladium-catalyzed cross-coupling and electrophilic substitution, respectively. Its bench-stable solid form facilitates handling, purification, and integration into multi-step sequences for pharmaceutical and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: