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Structure of 800401-71-2
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5-Bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid features a fused heterocyclic core with a bromo substituent at the 5-position and a carboxylic acid group at the 2-position. This combination enables direct incorporation into Suzuki-Miyaura coupling reactions and facilitates conjugation to biomolecules via amide bond formation. The electron-deficient pyrrolopyridine scaffold enhances reactivity in cross-coupling processes, while the carboxylic acid offers versatile derivatization potential under standard conditions.
5-Bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling. The bromo and carboxylic acid functionalities provide orthogonal reactivity for diversification, while the rigid fused scaffold enhances target binding affinity in medicinal chemistry applications. Bench-stable and compatible with standard purification methods, it facilitates scalable synthesis of pyrrolopyridine-based scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: