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CS-W001157 4
Total: USD 88.00

Fluocinolone

  • CAS No. 807-38-5

  • Cat. No. CS-0132766
  • Molecule weight412.42
  • Purity≥97%
  • MDL No.MFCD01699004

*For research and further manufacturing use only, not for direct human use.

Fluocinolone|CS-0132766

Structure of 807-38-5

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General Information

  • CAS No. 807-38-5
  • Cat. No. CS-0132766
  • Purity ≥97%
  • MDL No. MFCD01699004
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₆F₂O₆
  • Molecular Weight 412.42
  • Synonym(s) None
  • SMILES F[C@]([C@](C1=CC2=O)(C=C2)C)([C@H](C3)O)[C@](C[C@@H]1F)([H])[C@@](C[C@H]4O)([H])[C@]3([C@](O)4C(CO)=O)C

Description

Fluocinolone is a potent topical corticosteroid featuring a fluorinated cyclopentanoperhydrophenanthrene core, conferring high receptor affinity and anti-inflammatory activity. This compound exhibits strong efficacy in managing dermatological conditions such as eczema and psoriasis, offering rapid symptom relief with minimal systemic absorption due to its low dermal penetration profile.

Application

Fluocinolone serves as a potent topical corticosteroid with established anti-inflammatory and immunosuppressive activity. Its fluorinated structure enhances skin penetration and receptor binding affinity, enabling effective management of inflammatory dermatoses. The compound functions as a key intermediate in the synthesis of steroid-based therapeutics, offering stability and predictable reactivity in standard organic transformations.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   115.06
  • LogP   0.5685
  • H_Acceptors   6
  • H_Donors   4
  • Rotatable_Bonds   2

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