Fluocinolone

Name: Fluocinolone
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 807-38-5
Cat. No. CS-0132766
Purity≥97%
MDL No.MFCD01699004

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Fluocinolone is a potent topical corticosteroid featuring a fluorinated cyclopentanoperhydrophenanthrene core, conferring high receptor affinity and anti-inflammatory activity. This compound exhibits strong efficacy in managing dermatological conditions such as eczema and psoriasis, offering rapid symptom relief with minimal systemic absorption due to its low dermal penetration profile.

Application

Fluocinolone serves as a potent topical corticosteroid with established anti-inflammatory and immunosuppressive activity. Its fluorinated structure enhances skin penetration and receptor binding affinity, enabling effective management of inflammatory dermatoses. The compound functions as a key intermediate in the synthesis of steroid-based therapeutics, offering stability and predictable reactivity in standard organic transformations.

General Information

CAS No. 807-38-5
Cat. No. CS-0132766
Purity ≥97%
MDL No. MFCD01699004
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₆F₂O₆
Molecular Weight 412.42
Synonym(s) None
SMILES F[C@]([C@](C1=CC2=O)(C=C2)C)([C@H](C3)O)[C@](C[C@@H]1F)([H])[C@@](C[C@H]4O)([H])[C@]3([C@](O)4C(CO)=O)C

Computational Chemistry Data

TPSA 115.06
LogP 0.5685
H_Acceptors 6
H_Donors 4
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Bioactive Molecules Bioactive Small Molecules

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Fluocinolone

CAS No. 807-38-5

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