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Structure of 80826-86-4
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4-Iodo-3,5-dimethylphenol offers a sterically hindered phenolic scaffold with iodine at the para position relative to the hydroxyl group. The dimethyl substituents enhance electron density and stability, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. This bench-stable reagent integrates readily into complex molecular architectures requiring controlled functionalization.
4-Iodo-3,5-dimethylphenol serves as a versatile building block in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions. The iodine substituent enables efficient coupling under mild conditions, while the ortho-methyl groups provide steric and electronic stabilization. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures, including bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: