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CS-W001157 4
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Biotin-PEG1-NH2

  • CAS No. 811442-85-0

  • Cat. No. CS-0147801
  • Purity≥97%
  • MDL No.MFCD28397128

*For research and further manufacturing use only, not for direct human use.

Biotin-PEG1-NH2|CS-0147801

Structure of 811442-85-0

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General Information

  • CAS No. 811442-85-0
  • Cat. No. CS-0147801
  • Purity ≥97%
  • MDL No. MFCD28397128
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₆N₄O₃S
  • Molecular Weight 330.45
  • Synonym(s) None
  • SMILES NCCOCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O

Description

Biotin-PEG1-NH2 features a short polyethylene glycol spacer linking biotin to a primary amine group. This structure enables efficient conjugation to biomolecules or surfaces via amide bond formation, while the PEG moiety enhances solubility and reduces non-specific binding in biological applications.

Application

Biotin-PEG1-NH₂ serves as a versatile bifunctional linker for bioconjugation, enabling site-specific attachment of biotinylated molecules to amine-containing targets. The short PEG spacer enhances solubility and reduces steric hindrance, while the primary amine facilitates efficient coupling under standard conditions. This reagent is bench-stable, readily purified by precipitation or chromatography, and widely used in affinity purification, immunoassays, and targeted delivery systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   105.48
  • LogP   -0.1963
  • H_Acceptors   5
  • H_Donors   4
  • Rotatable_Bonds   10

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