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Structure of 81226-68-8
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5-Bromo-2-chlorobenzene-1-sulfonyl chloride features a sulfonyl chloride group flanked by bromo and chloro substituents on a benzene ring, enabling selective electrophilic functionalization. This electron-deficient aryl sulfonyl chloride integrates readily into pharmaceutical intermediates and specialty materials, offering high reactivity under mild conditions with excellent chemoselectivity in amine coupling reactions.
5-Bromo-2-chlorobenzene-1-sulfonyl chloride serves as a versatile building block for the synthesis of sulfonamide-containing pharmaceutical intermediates and functionalized heterocycles. Its dual halogenation pattern enables selective cross-coupling reactions, while the sulfonyl chloride group facilitates facile derivatization via nucleophilic substitution. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P280-P301+P330+P331-P304+P340
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Lot numbers can be found on the outside label of a product: