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Structure of 81228-09-3
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2,4-Difluorophenylacetic acid has been used in the synthesis of nonpolar peptide nucleic acid monomers containing fluoroaromatics (F-PNA).
2-(2,4-Difluorophenyl)acetic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard functional group transformations. Its difluorophenyl moiety enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality facilitates direct coupling or derivatization. The compound exhibits excellent bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: