5'-O-DMT-Bz-rA

Name: 5'-O-DMT-Bz-rA
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 81246-82-4
Cat. No. CS-D1777
Purity≥95%
MDL No.MFCD00797466

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 81246-82-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5'-O-DMT-Bz-rA delivers a protected riboadenosine building block with enhanced solubility and stability in synthetic workflows. The DMT group at the 5'-position provides robust protection during oligonucleotide assembly, while the benzoyl moiety at the N6 position ensures high-fidelity incorporation. This derivative simplifies purification and supports efficient coupling under standard conditions.

Application

5'-O-DMT-Bz-rA serves as a key building block in oligonucleotide synthesis, enabling the site-specific incorporation of a benzoyl-modified ribo-adenosine residue. The DMT group provides orthogonal protection at the 5'-end, facilitating efficient purification by acid-labile deprotection and allowing selective chain elongation. The benzoyl modification at the N6 position enhances duplex stability through improved base stacking and offers compatibility with standard phosphoramidite coupling protocols. This derivative exhibits robust bench stability and facilitates straightforward purification, making it well-suited for the synthesis of modified RNA constructs in therapeutic and diagnostic applications.

General Information

CAS No. 81246-82-4
Cat. No. CS-D1777
Purity ≥95%
MDL No. MFCD00797466
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₈H₃₅N₅O₇
Molecular Weight 673.71
Synonym(s) None
SMILES O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@@H]1COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7

Computational Chemistry Data

TPSA 150.08
LogP 4.7237
H_Acceptors 11
H_Donors 3
Rotatable_Bonds 11

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Life Science Nucleosides & Nucleotides Other Protective Nucleosides

Chemical Biology Nucleic Acid Chemistry Protected Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

Key Words

5'-O-DMT-Bz-rA sigma5'-O-DMT-Bz-rA manufacturer5'-O-DMT-Bz-rA price5'-O-DMT-Bz-rA structure5'-O-DMT-Bz-rA SDSbuy 5'-O-DMT-Bz-rA5'-O-DMT-Bz-rA supplier5'-O-DMT-Bz-rA uses5'-O-DMT-Bz-rA molecular weightprice of 5'-O-DMT-Bz-rA5'-O-DMT-Bz-rA chemical name formula of 5'-O-DMT-Bz-rA

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5'-O-DMT-Bz-rA

CAS No. 81246-82-4

Recommended Products