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CS-W001157 4
Total: USD 88.00

DSPC

  • CAS No. 816-94-4

  • Cat. No. CS-W020933
  • Molecule weight790.15
  • Purity≥98%
  • MDL No.MFCD00036905

*For research and further manufacturing use only, not for direct human use.

DSPC|CS-W020933

Structure of 816-94-4

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General Information

  • CAS No. 816-94-4
  • Cat. No. CS-W020933
  • Purity ≥98%
  • MDL No. MFCD00036905
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₄H₈₈NO₈P
  • Molecular Weight 790.15
  • Synonym(s) 1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
  • SMILES O=P([O-])(OCC[N+](C)(C)C)OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O

Description

Intercalating into lipid bilayers with high phase transition stability, 18:0 PC (DSPC) (CAS 816-94-4) maintains membrane integrity across physiological temperature gradients due to its saturated C18 acyl chains and conserved phosphocholine moiety.

Application

18:0 PC (DSPC) (CAS 816-94-4) drives microbubble formation by stabilizing lipid shells under high shear stress, enabling precise ultrasound contrast enhancement. It also forms robust unilamellar vesicles. Researchers leverage this phospholipid to deliver methylene blue efficiently via liposomes, ensuring controlled release and improved bioavailability in targeted imaging applications.

Synthesis

  • Route1
    • Vinyl stearate|CS-0167847
      111-63-7
    • null|null
      34688-34-1
    • ~%
    • In-stock
      DSPC|CS-W020933
      816-94-4
    • 1-Stearoyl-lysophosphatidylcholine|CS-1660545
      17364-19-1
    • null|null
      57-11-4

    References

    • US7034168 B2, ; Page/Page column 16 ;
  • Route2

    References

    • J. Gen. Chem. USSR (Engl. Transl.), , vol. 32, # 7 p. 2210 - 2214,2177 - 2180
  • Route3
    • 1,2-Dilinoleoyl-sn-glycero-3-PC|CS-0902937
      6542-05-8
    • ~%
    • In-stock
      DSPC|CS-W020933
      816-94-4

    References

    • J. Gen. Chem. USSR (Engl. Transl.), , vol. 34, p. 1908 - 1911,1921 - 1923

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   111.19
  • LogP   12.1722
  • H_Acceptors   8
  • H_Donors   0
  • Rotatable_Bonds   42

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