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Structure of 81769-69-9
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1-Methyl-4-(trifluoromethyl)-1H-imidazole features a trifluoromethyl group that imparts strong electron-withdrawing character and enhanced metabolic stability. This bench-stable heterocycle integrates readily into medicinal chemistry scaffolds, offering improved solubility and lipophilicity profiles for target-directed drug design.
1-Methyl-4-(trifluoromethyl)-1H-imidazole serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its electron-deficient imidazole core enables reliable coupling reactions and facilitates functionalization at the 2-position. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the N-methyl substitution improves solubility and synthetic handling. This compound functions as a key scaffold for bioactive molecule development and is compatible with standard cross-coupling and electrophilic substitution protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: