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CS-W001157 4
Total: USD 88.00

Diphenyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine

  • CAS No. 819867-23-7

  • Cat. No. CS-0040932
  • Purity≥95%
  • MDL No.MFCD26961066

*For research and further manufacturing use only, not for direct human use.

Diphenyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine|CS-0040932

Structure of 819867-23-7

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General Information

  • CAS No. 819867-23-7
  • Cat. No. CS-0040932
  • Purity ≥95%
  • MDL No. MFCD26961066
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₃H₃₇P
  • Molecular Weight 464.62
  • Synonym(s) Phosphine, diphenyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]-
  • SMILES CC(C)C1=CC(C(C)C)=CC(C(C)C)=C1C2=C(P(C3=CC=CC=C3)C4=CC=CC=C4)C=CC=C2

Description

Diphenyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine features a sterically shielded phosphine moiety that enhances stability and reactivity in catalytic applications. The bulky triisopropylbiphenyl group imparts exceptional resistance to oxidation, enabling reliable performance under air-sensitive conditions. This ligand integrates seamlessly into palladium-catalyzed cross-coupling reactions, delivering high efficiency and selectivity across diverse substrates.

Application

Diphenyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine serves as a sterically encumbered, bench-stable phosphine ligand that enables efficient cross-coupling reactions in palladium-catalyzed processes. Its bulky triisopropylbiphenyl moiety enhances catalyst stability and promotes reductive elimination, facilitating challenging C–C and C–heteroatom bond formations. The ligand exhibits excellent functional group tolerance and simplifies purification due to its high solubility and resistance to oxidation.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   8.482
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   7

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