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Structure of 824943-40-0
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This chiral piperidine derivative features a hydroxyl group at the 5-position and a carboxylic acid at the 2-position, stabilized as the hydrochloride salt. The stereochemistry at C2 and C5 imparts distinct conformational rigidity, enhancing its utility in medicinal chemistry for probing bioactive ligand-receptor interactions. Bench-stable and readily soluble in aqueous systems, it serves as a key building block for peptide mimetics and CNS-targeted small molecules.
(2S,5R)-5-Hydroxypiperidine-2-carboxylic acid hydrochloride serves as a stereochemically defined building block for the synthesis of bioactive heterocycles and peptidomimetics. Its well-defined stereocenters enable predictable conformational control in medicinal chemistry applications. The molecule exhibits favorable bench stability, moderate solubility in protic solvents, and tolerance to standard coupling conditions, facilitating efficient incorporation into complex scaffolds via amide bond formation or cyclization reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P341-P312-P330-P363-P501
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Lot numbers can be found on the outside label of a product: