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Structure of 825-98-9
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3-Fluoro-4-iodobenzoic acid features a fluorinated aromatic ring paired with iodine and carboxylic acid functional groups, enabling direct coupling in cross-coupling reactions. The electron-withdrawing fluorine enhances reactivity, while the iodide serves as a robust handle for palladium-catalyzed transformations. This compound integrates seamlessly into complex molecular architectures requiring precise substitution patterns.
3-Fluoro-4-iodobenzoic acid serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The ortho-fluoro and para-iodo substituents offer complementary reactivity for sequential functionalization, while the carboxylic acid group facilitates derivatization or direct incorporation into pharmaceutical intermediates. Its bench-stable crystalline form simplifies handling and purification in synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: