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Structure of 82972-28-9
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Methyl 3-(piperazin-1-yl)propanoate dihydrochloride is a bench-stable, moisture-tolerant reagent featuring a piperazine moiety linked to a propanoate ester. This polar, protonated derivative enhances solubility in aqueous and protic solvents, enabling efficient incorporation into peptide conjugation and medicinal chemistry workflows.
Methyl 3-(piperazin-1-yl)propanoate dihydrochloride serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of piperazine-containing scaffolds. The piperazinyl group provides enhanced solubility and hydrogen-bonding capacity, while the ester functionality supports downstream transformations such as hydrolysis, amidation, or coupling reactions. Its dihydrochloride salt form enhances stability and facilitates purification, making it well-suited for use in multi-step synthetic sequences targeting bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: