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Structure of 83141-10-0
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2,6-Difluoro-3-nitrobenzoic acid features a strategically positioned nitro group and two fluorine substituents that enhance electrophilicity and metabolic stability. This electron-deficient aromatic core integrates readily into synthetic routes requiring strong acceptor moieties. The carboxylic acid functionality enables direct coupling or derivatization under standard conditions.
2,6-Difluoro-3-nitrobenzoic acid serves as a versatile building block in medicinal chemistry, enabling direct introduction of fluorinated aromatic scaffolds with orthogonal functional handles. The carboxylic acid facilitates amide coupling and esterification, while the nitro group offers a reliable handle for reduction to aniline derivatives. Fluorine substituents enhance metabolic stability and modulate electronic properties, making this compound well-suited for constructing bioactive heterocycles and drug-like molecules under standard synthetic conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: