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Structure of 83507-33-9
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3-Benzyl-3-azabicyclo[3.2.1]octan-8-one features a rigid, nitrogen-containing bicyclic scaffold that imparts structural constraint and enhanced metabolic stability. The benzyl group provides π-stacking potential, while the ketone functionality enables direct functionalization or conjugation. This compound serves as a high-value scaffold in medicinal chemistry for probing receptor-ligand interactions and constructing bioactive molecules with defined spatial orientation.
3-Benzyl-3-azabicyclo[3.2.1]octan-8-one serves as a rigid, conformationally constrained scaffold for medicinal chemistry campaigns, enabling precise spatial positioning of functional groups. Its tertiary amine and ketone functionalities offer orthogonal reactivity for derivatization via reductive amination, nucleophilic addition, or enolate formation. The bicyclic core exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis and lead optimization in CNS-targeted drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: