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CS-W001157 4
Total: USD 88.00

3,7-Dihydroxy-2-naphthoic acid

  • CAS No. 83511-07-3

  • Cat. No. CS-W015418
  • Purity≥95%
  • MDL No.MFCD00010253

*For research and further manufacturing use only, not for direct human use.

3,7-Dihydroxy-2-naphthoic acid|CS-W015418

Structure of 83511-07-3

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General Information

  • CAS No. 83511-07-3
  • Cat. No. CS-W015418
  • Purity ≥95%
  • MDL No. MFCD00010253
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈O₄
  • Molecular Weight 204.18
  • Synonym(s) 3,7-dihydroxynaphthalene-2-carboxylic acid
  • SMILES OC(=O)C1=CC2=C(C=CC(O)=C2)C=C1O

Description

3,7-Dihydroxy-2-naphthoic acid served as a substrate for the enzyme NcsB1 (an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin) in the NcsB1-catalyzed O-methylation of 2,7-dihydroxy-5-methyl-1-naphthoic acid.3,7-Dihydroxy-2-naphthoic acid was used in the synthesis of 3-hydroxy-7-methoxy-2-naphthoic acid.

Synthesis

  • Route1
    • null|null
      26513-28-0
    • ~80%
    • 3,7-Dihydroxy-2-naphthoic acid|CS-W015418
      83511-07-3

    References

    • Jarvi, Esa T.; Whitlock, Howard W. Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7196 - 7204
  • Route2
    • null|null
      92-70-6
    • ~%
    • 3,7-Dihydroxy-2-naphthoic acid|CS-W015418
      83511-07-3

    References

    • Journal of the American Chemical Society, , vol. 104, # 25 p. 7196 - 7204
  • Route3
    • null|null
      15509-36-1
    • ~%
    • 3,7-Dihydroxy-2-naphthoic acid|CS-W015418
      83511-07-3

    References

    • Chemische Berichte, , vol. 26, p. 1121 DE69357 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 506

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

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Computational Chemistry Data

  • TPSA   77.76
  • LogP   1.9492
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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