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Structure of 835882-02-5
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N-(2-Bromopyridin-3-yl)pivalamide features a sterically shielded pivaloyl group attached to a bromopyridine nitrogen, enhancing stability and facilitating selective functionalization. This bench-stable derivative enables direct coupling in transition-metal-catalyzed cross-coupling reactions, serving as a robust building block for complex heterocyclic architectures in medicinal chemistry and materials science.
N-(2-Bromopyridin-3-yl)pivalamide serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, particularly in the construction of biaryl and heteroaryl scaffolds. The bromopyridine moiety enables efficient Pd-catalyzed coupling with boronic acids and other nucleophiles, while the pivalamide group provides steric protection and enhanced bench stability. Its functional group tolerance and ease of purification make it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: