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Structure of 837392-62-8
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1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is a bench-stable boronate ester featuring a sterically shielded dioxaborolane group attached to an electron-rich indole core. This structure enables efficient Suzuki-Miyaura coupling reactions under mild conditions, facilitating the rapid construction of biaryl architectures in medicinal chemistry and materials synthesis. The tetramethyl-substituted boronate moiety enhances hydrolytic stability and compatibility with aqueous reaction media.
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient palladium-catalyzed coupling with aryl and heteroaryl halides under mild conditions. Its indole core provides a versatile scaffold for medicinal chemistry and materials science applications, offering excellent functional group tolerance and straightforward purification due to low background reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: