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Structure of 83766-88-5
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2-tert-Butoxypyridine features a sterically hindered tert-butoxy group at the pyridine ring's 2-position, enhancing its stability and resistance to hydrolysis. This electron-donating substituent modulates the ring’s electronic properties, enabling selective functionalization in cross-coupling reactions. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, facilitating its integration into complex synthetic sequences.
2-tert-Butoxypyridine serves as a versatile building block in synthetic organic chemistry, enabling regioselective functionalization at the pyridine C2 position. Its tert-butyl ether group provides enhanced bench stability and facilitates subsequent deprotection under mild acidic conditions. The molecule exhibits excellent functional group tolerance and functions effectively in palladium-catalyzed cross-coupling reactions, making it valuable for constructing complex heterocyclic scaffolds and advanced intermediates in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: