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CS-W001157 4
Total: USD 88.00

2-(4-Bromophenyl)quinazolin-4(3h)-one

  • CAS No. 83800-88-8

  • Cat. No. CS-0349340
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-Bromophenyl)quinazolin-4(3h)-one|CS-0349340

Structure of 83800-88-8

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General Information

  • CAS No. 83800-88-8
  • Cat. No. CS-0349340
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₉BrN₂O
  • Molecular Weight 301.14
  • Synonym(s) None
  • SMILES O=C1NC(C2=CC=C(Br)C=C2)=NC3=C1C=CC=C3

Description

2-(4-Bromophenyl)quinazolin-4(3H)-one features a brominated phenyl group appended to the quinazoline core, enhancing electron-withdrawing character and enabling diverse synthetic transformations. This scaffold exhibits robust stability under standard conditions and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibition pathways.

Application

2-(4-Bromophenyl)quinazolin-4(3H)-one serves as a versatile building block for the synthesis of biologically active quinazoline derivatives. Its bromo substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of complex heterocyclic scaffolds. The molecule exhibits good bench stability and functional group tolerance, making it suitable for iterative medicinal chemistry campaigns and API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   3.3526
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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