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CS-W001157 4
Total: USD 88.00

4-(Methylsulfonamido)benzaldehyde

  • CAS No. 83922-54-7

  • Cat. No. CS-W004024
  • Purity≥97%
  • MDL No.MFCD11052340

*For research and further manufacturing use only, not for direct human use.

4-(Methylsulfonamido)benzaldehyde|CS-W004024

Structure of 83922-54-7

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General Information

  • CAS No. 83922-54-7
  • Cat. No. CS-W004024
  • Purity ≥97%
  • MDL No. MFCD11052340
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃S
  • Molecular Weight 199.23
  • Synonym(s) N-(4-Formylphenyl)methanesulfonamide
  • SMILES CS(NC1=CC=C(C=O)C=C1)(=O)=O

Description

for biochemistryL-Methionine for biochemistry. CAS 63-68-3, pH 5-7 (10g/l, HO, 20C).

Application

4-(Methylsulfonamido)benzaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its aldehyde functionality facilitates efficient condensation reactions, while the methylsulfonamide group provides enhanced solubility and hydrogen-bonding capacity. The compound exhibits good bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1
    • N-(4-(Hydroxymethyl)phenyl)methanesulfonamide|CS-0099929
      774238-85-6
    • ~66%
    • In-stock
      4-(Methylsulfonamido)benzaldehyde|CS-W004024
      83922-54-7

    References

    • BAYER PHARMACEUTICALS CORPORATION Patent: WO2004/94376 A1, 2004 ; Location in patent: Page 308 ;
  • Route2

    References

    • Rosen, Brandon R.; Ruble, J. Craig; Beauchamp, Thomas J.; Navarro, Antonio Organic Letters, 2011 , vol. 13, # 10 p. 2564 - 2567
  • Route3
    • 4-(1,3-Dioxolan-2-yl)aniline|CS-0180900
      19073-14-4
    • null|null
      124-63-0
    • ~42%
    • In-stock
      4-(Methylsulfonamido)benzaldehyde|CS-W004024
      83922-54-7

    References

    • UNION CARBIDE CHEMICALS and PLASTICS TECHNOLOGY CORPORATION Patent: WO2005/77884 A2, 2005 ; Location in patent: Page/Page column 17 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.24
  • LogP   0.8706
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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