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Structure of 83942-13-6
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4-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine features a fused bicyclic core with a chlorine substituent at the 4-position, enabling direct incorporation into heterocyclic scaffolds. This bench-stable, moisture-tolerant building block facilitates efficient access to functionalized pyrimidine derivatives through palladium-catalyzed cross-coupling or nucleophilic substitution reactions.
4-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine serves as a versatile building block for the synthesis of biologically active heterocycles, particularly in medicinal chemistry. Its reactive chlorine substituent enables facile nucleophilic substitution, facilitating the construction of diverse pyrimidine-based scaffolds. The saturated cyclopentane ring enhances metabolic stability and modulates physicochemical properties, supporting its use in lead optimization. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: