Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4'-Benzyloxyphenyl acetylene

  • CAS No. 84284-70-8

  • Cat. No. CS-0158561
  • Purity≥97%
  • MDL No.MFCD01814885

*For research and further manufacturing use only, not for direct human use.

4'-Benzyloxyphenyl acetylene|CS-0158561

Structure of 84284-70-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 84284-70-8
  • Cat. No. CS-0158561
  • Purity ≥97%
  • MDL No. MFCD01814885
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₂O
  • Molecular Weight 208.26
  • Synonym(s) Benzyl 4-ethynylphenyl ether
  • SMILES C#CC1=CC=C(C=C1)OCC2=CC=CC=C2

Description

4'-Benzyloxyphenyl acetylene features a para-benzyloxy-substituted phenyl ring linked to an acetylene handle, enabling efficient copper-catalyzed coupling reactions. The benzyl ether group enhances solubility and stability under standard conditions, while the terminal alkyne facilitates conjugation in functional materials and bioconjugation workflows.

Application

4'-Benzyloxyphenyl acetylene serves as a versatile building block for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling efficient access to triazole-linked molecular architectures. The benzyloxy group provides orthogonal protection and enhances solubility, while the terminal alkyne exhibits high reactivity under standard click chemistry conditions. This compound demonstrates excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      114943-73-6
    • ~96%
    • In-stock
      4'-Benzyloxyphenyl acetylene|CS-0158561
      84284-70-8

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 11 p. 3125 - 3127
  • Route2
    • ((4-(Benzyloxy)phenyl)ethynyl)trimethylsilane|CS-0663105
      340322-86-3
    • ~99%
    • In-stock
      4'-Benzyloxyphenyl acetylene|CS-0158561
      84284-70-8

    References

    • ChemMedChem, , vol. 5, # 8 p. 1236 - 1241
  • Route3
    • In-stock
      1-(Benzyloxy)-4-iodobenzene|CS-0196948
      19578-68-8
    • null|null
      1066-54-2
    • ~%
    • In-stock
      4'-Benzyloxyphenyl acetylene|CS-0158561
      84284-70-8

    References

    • WO2005/775 A2, ; Page 41-43 ; WO 2005/000775 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.2469
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4'-Benzyloxyphenyl acetylene sigma4'-Benzyloxyphenyl acetylene manufacturer4'-Benzyloxyphenyl acetylene price4'-Benzyloxyphenyl acetylene structure4'-Benzyloxyphenyl acetylene SDSbuy 4'-Benzyloxyphenyl acetylene4'-Benzyloxyphenyl acetylene supplier4'-Benzyloxyphenyl acetylene uses4'-Benzyloxyphenyl acetylene molecular weightprice of 4'-Benzyloxyphenyl acetylene4'-Benzyloxyphenyl acetylene chemical name formula of 4'-Benzyloxyphenyl acetylene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label