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CS-W001157 4
Total: USD 88.00

Quinoxaline-5-sulfonyl chloride

  • CAS No. 844646-88-4

  • Cat. No. CS-0110639
  • Purity≥97%
  • MDL No.MFCD12827951
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Quinoxaline-5-sulfonyl chloride|CS-0110639

Structure of 844646-88-4

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Description

Quinoxaline-5-sulfonyl chloride features a reactive sulfonyl chloride group appended to a quinoxaline core, enabling efficient conjugation in synthetic transformations. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering enhanced stability under standard conditions while maintaining high reactivity for nucleophilic substitution.

Application

Quinoxaline-5-sulfonyl chloride serves as a versatile building block for the synthesis of functionalized heterocycles and bioactive molecules. Its sulfonyl chloride group enables efficient coupling reactions with amines and alcohols, facilitating the construction of sulfonamide and sulfonate derivatives under mild conditions. The quinoxaline core provides a rigid, electron-deficient platform suitable for pharmaceutical and agrochemical applications. The reagent exhibits good bench stability and is readily purified by crystallization, enhancing its utility in iterative synthetic sequences.

General Information

  • CAS No. 844646-88-4
  • Cat. No. CS-0110639
  • Purity ≥97%
  • MDL No. MFCD12827951
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅ClN₂O₂S
  • Molecular Weight 228.66
  • Synonym(s) 5-Quinoxalinesulfonylchloride
  • SMILES O=S(C1=C2N=CC=NC2=CC=C1)(Cl)=O

Computational Chemistry Data

  • TPSA   59.92
  • LogP   1.5573
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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