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CS-W001157 4
Total: USD 88.00

3-Fluoro-5-iodobromobenzene

  • CAS No. 845866-85-5

  • Cat. No. CS-W021920
  • Purity≥98%
  • MDL No.MFCD06657969
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-5-iodobromobenzene|CS-W021920

Structure of 845866-85-5

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Description

3-Fluoro-5-iodobromobenzene is a trifunctional aryl halide featuring fluorine, iodine, and bromine substituents at meta and para positions relative to one another. This electron-deficient scaffold enables selective cross-coupling reactions in late-stage functionalization. The molecule exhibits enhanced stability under standard handling conditions and integrates readily into transition metal-catalyzed transformations.

Application

3-Fluoro-5-iodobromobenzene serves as a versatile diaryl building block in palladium-catalyzed cross-coupling reactions, enabling efficient synthesis of functionalized biaryls and heterocyclic scaffolds. The ortho-fluoro substituent facilitates directed metallation and subsequent functionalization, while the iodide and bromide groups offer complementary reactivity for sequential coupling processes. Bench-stable and compatible with standard reaction conditions, it supports precise molecular diversification in medicinal chemistry and materials science applications.

General Information

  • CAS No. 845866-85-5
  • Cat. No. CS-W021920
  • Purity ≥98%
  • MDL No. MFCD06657969
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrFI
  • Molecular Weight 300.90
  • Synonym(s) Benzene, 1-bromo-3-fluoro-5-iodo-
  • SMILES BrC1=CC(=CC(=C1)I)F

Computational Chemistry Data

  • TPSA   0
  • LogP   3.1928
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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