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Structure of 845866-85-5
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3-Fluoro-5-iodobromobenzene is a trifunctional aryl halide featuring fluorine, iodine, and bromine substituents at meta and para positions relative to one another. This electron-deficient scaffold enables selective cross-coupling reactions in late-stage functionalization. The molecule exhibits enhanced stability under standard handling conditions and integrates readily into transition metal-catalyzed transformations.
3-Fluoro-5-iodobromobenzene serves as a versatile diaryl building block in palladium-catalyzed cross-coupling reactions, enabling efficient synthesis of functionalized biaryls and heterocyclic scaffolds. The ortho-fluoro substituent facilitates directed metallation and subsequent functionalization, while the iodide and bromide groups offer complementary reactivity for sequential coupling processes. Bench-stable and compatible with standard reaction conditions, it supports precise molecular diversification in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: