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CS-W001157 4
Total: USD 88.00

3-(Ethylsulfonyl)phenylboronic acid

  • CAS No. 845870-47-5

  • Cat. No. CS-0007635
  • Purity≥95%
  • MDL No.MFCD03095257
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(Ethylsulfonyl)phenylboronic acid|CS-0007635

Structure of 845870-47-5

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Description

3-(Ethylsulfonyl)phenylboronic acid delivers a robust boronate handle flanked by an electron-withdrawing ethylsulfonyl group, enhancing stability and tuning reactivity in Suzuki-Miyaura coupling. This bench-stable reagent integrates readily into complex molecule synthesis under standard conditions.

Application

3-(Ethylsulfonyl)phenylboronic acid serves as a robust building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced solubility and metabolic stability. The ethylsulfonyl group confers excellent bench stability, mild functional group tolerance, and facilitates purification via standard chromatographic methods. Its compatibility with diverse reaction conditions makes it a practical choice for medicinal chemistry and process development workflows.

General Information

  • CAS No. 845870-47-5
  • Cat. No. CS-0007635
  • Purity ≥95%
  • MDL No. MFCD03095257
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄S
  • Molecular Weight 214.05
  • Synonym(s) 3-Ethylsulfonylphenylboronic acid
  • SMILES O=S(C1=CC(B(O)O)=CC=C1)(CC)=O

Computational Chemistry Data

  • TPSA   74.6
  • LogP   -0.84
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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