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Structure of 845885-90-7
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4-Fluoro-3-formylbenzoic acid features a formyl group ortho to a carboxylic acid and para to a fluorine atom, enabling selective coupling in synthetic sequences. This electron-deficient aromatic scaffold integrates readily into complex architectures, offering enhanced reactivity in transition-metal-catalyzed transformations and facilitating downstream functionalization via nucleophilic addition or condensation reactions.
4-Fluoro-3-formylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both formyl and carboxylic acid functionalities for downstream derivatization. Its ortho-directed reactivity facilitates efficient heterocycle formation, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard purification methods, making it well-suited for multi-step synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: