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CS-W001157 4
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2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid

  • CAS No. 84627-04-3

  • Cat. No. CS-0468443
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid|CS-0468443

Structure of 84627-04-3

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Description

This biphenyl-based carboxylic acid features a hydroxyl group at the 6-position of the phenyl ring, enhancing solubility and enabling hydrogen bonding. The para-substituted benzoic acid moiety provides a rigid, electron-deficient platform ideal for conjugate addition reactions and molecular scaffold integration in medicinal chemistry.

Application

2-(6-Hydroxy-[1,1'-biphenyl]-3-carbonyl)benzoic acid serves as a versatile building block for constructing biaryl-containing scaffolds in medicinal chemistry and materials science. The molecule combines a carboxylic acid functionality with a phenolic hydroxyl group, enabling diverse derivatization via amide, ester, or ether formation. Its biphenyl core offers structural rigidity and π-conjugation, while the ortho-carbonyl substitution pattern supports controlled reactivity in coupling and cyclization reactions. This compound demonstrates bench stability and compatibility with standard purification methods, facilitating integration into multi-step synthetic sequences.

General Information

  • CAS No. 84627-04-3
  • Cat. No. CS-0468443
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₄O₄
  • Molecular Weight 318.32
  • Synonym(s) Fendizoic acid
  • SMILES O=C(O)C1=CC=CC=C1C(C2=CC(C3=CC=CC=C3)=C(O)C=C2)=O

Computational Chemistry Data

  • TPSA   74.6
  • LogP   3.9884
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319-H412
Precautionary Statements : P264-P270-P273-P280-P330-P501

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