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Structure of 847490-69-1
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4-Iodoisoxazole is a bench-stable heterocycle featuring a reactive iodine substituent at the 4-position, enabling direct functionalization in cross-coupling processes. This electron-deficient isoxazole integrates readily into complex molecular architectures, offering predictable regiochemistry and compatibility with palladium-catalyzed transformations under standard conditions.
4-Iodoisoxazole serves as a versatile building block for constructing nitrogen-containing heterocycles, enabling direct transition-metal-catalyzed coupling reactions due to its stable C–I bond. It functions as a reliable electrophilic partner in cross-coupling protocols, offering high functional group tolerance and bench stability. Its utility extends to the synthesis of bioactive scaffolds in medicinal chemistry, where it facilitates rapid diversification through palladium- or nickel-mediated transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: