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CS-W001157 4
Total: USD 88.00

(S)-Ethyl 2-((S)-4-methyl-2,5-dioxooxazolidin-3-yl)-4-phenylbutanoate Enalapril Impurity

  • CAS No. 84793-24-8

  • Cat. No. CS-0229436
  • Purity≥98%
  • MDL No.MFCD00272296

*For research and further manufacturing use only, not for direct human use.

(S)-Ethyl 2-((S)-4-methyl-2,5-dioxooxazolidin-3-yl)-4-phenylbutanoate Enalapril  Impurity|CS-0229436

Structure of 84793-24-8

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General Information

  • CAS No. 84793-24-8
  • Cat. No. CS-0229436
  • Purity ≥98%
  • MDL No. MFCD00272296
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₉NO₅
  • Molecular Weight 305.33
  • Synonym(s) N-[1-(S)-Ethoxycarbonyl-3-Phenylpropyl]-N-Carboxy-L-Alanine Anhydride (Nepa-Nca)
  • SMILES O=C(OCC)[C@@H](N([C@H]1C)C(OC1=O)=O)CCC2=CC=CC=C2

Synthesis

  • Route1
    • (S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoic acid Enalapril  Impurity|CS-0229435
      82717-96-2
    • null|null
      530-62-1
    • ~%
    • (S)-Ethyl 2-((S)-4-methyl-2,5-dioxooxazolidin-3-yl)-4-phenylbutanoate Enalapril  Impurity|CS-0229436
      84793-24-8

    References

    • US2006/79698 A1, ; Page/Page column 6 ;
  • Route2
    • null|null
      32315-10-9
    • (S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoic acid Enalapril  Impurity|CS-0229435
      82717-96-2
    • ~%
    • (S)-Ethyl 2-((S)-4-methyl-2,5-dioxooxazolidin-3-yl)-4-phenylbutanoate Enalapril  Impurity|CS-0229436
      84793-24-8

    References

    • WO2005/51909 A1, ; Page/Page column 6; 18; 20 ;
  • Route3
    • null|null
      75-44-5
    • (S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoic acid Enalapril  Impurity|CS-0229435
      82717-96-2
    • ~%
    • (S)-Ethyl 2-((S)-4-methyl-2,5-dioxooxazolidin-3-yl)-4-phenylbutanoate Enalapril  Impurity|CS-0229436
      84793-24-8

    References

    • European Journal of Medicinal Chemistry, , vol. 20, # 6 p. 563 - 570

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.91
  • LogP   1.9182
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   6

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