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Structure of 848953-05-9
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3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile features a boronate ester group paired with a nitrile and methyl substituent on a phenyl ring. This combination enables direct coupling in Suzuki-Miyaura reactions under standard conditions. The tetramethyl-substituted dioxaborolane enhances stability and reactivity while minimizing protodeboronation. It serves as a key building block for functionalized aryl targets in medicinal chemistry and materials synthesis.
3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The nitrile group provides synthetic handle for downstream transformations, while the sterically protected boronate ester ensures excellent shelf stability and functional group tolerance. Its compatibility with diverse coupling partners enables efficient construction of biaryl scaffolds relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: