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Structure of 850313-92-7
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Potassium trifluoro(2-hydroxyphenyl)borate features a boronate group flanked by a phenolic hydroxyl, enhancing solubility and stability in aqueous media. This bench-stable reagent facilitates direct C–C bond formation under mild conditions, enabling efficient coupling in Suzuki-Miyaura reactions. The ortho-hydroxy functionality enables chelation-assisted activation, improving reaction kinetics and selectivity.
Potassium trifluoro(2-hydroxyphenyl)borate serves as a stable, bench-ready boron source for Suzuki-Miyaura cross-coupling reactions. The ortho-hydroxyphenyl group enhances regioselective coupling and facilitates in situ stabilization of the boronate intermediate. It exhibits good functional group tolerance and enables efficient C–C bond formation under mild conditions, making it a practical building block for biaryl scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: