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CS-W001157 4
Total: USD 88.00
  • CAS No. 85073-19-4

  • Cat. No. CS-0102459
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD29472537

*For research and further manufacturing use only, not for direct human use.

LAP|CS-0102459

Structure of 85073-19-4

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General Information

  • CAS No. 85073-19-4
  • Cat. No. CS-0102459
  • Purity ≥97%
  • MDL No. MFCD29472537
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₆LiO₃P
  • Molecular Weight None
  • Synonym(s) Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
  • SMILES O=P(C(C1=C(C)C=C(C)C=C1C)=O)(C2=CC=CC=C2)O[Li]

Application

LAP serves as a reliable, bench-stable reagent for the selective deprotection of phosphoramidite-protected oligonucleotides and nucleoside derivatives. It facilitates efficient removal of phosphate protecting groups under mild conditions, enabling high-yielding synthesis of defined oligonucleotide sequences with minimal side reactions. Its compatibility with diverse nucleoside scaffolds and ease of handling make it a practical choice for solid-phase and solution-phase DNA/RNA synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P330-P302+P352-P304+P340-P305+P351+P338-P332+P317-P362+P364-P337+P317-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   3.45576
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

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