(R)-3-Phenylpyrrolidine hydrochloride

Name: (R)-3-Phenylpyrrolidine hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 851000-46-9
Cat. No. CS-W019085
Purity≥97%
MDL No.MFCD06796636

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-3-Phenylpyrrolidine hydrochloride|CS-W019085

Structure of 851000-46-9

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Description

(R)-3-Phenylpyrrolidine hydrochloride is a stereochemically defined heterocyclic amine featuring a phenyl-substituted pyrrolidine core. This bench-stable salt form enhances solubility and handling, enabling straightforward integration into asymmetric synthesis workflows. The chiral center facilitates enantioselective transformations in medicinal chemistry and catalyst design.

Application

(R)-3-Phenylpyrrolidine hydrochloride serves as a stereochemically defined building block for the synthesis of bioactive amines and pharmaceutical intermediates. Its stable, crystalline form facilitates handling and purification, while the pyrrolidine core enables efficient functionalization at C3 and N1 positions. The compound reacts readily in standard coupling and reductive amination protocols, offering broad utility in medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors.

General Information

CAS No. 851000-46-9
Cat. No. CS-W019085
Purity ≥97%
MDL No. MFCD06796636
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₄ClN
Molecular Weight None
Synonym(s) (R)-3-PHENYL-PYRROLIDINE HYDROCHLORIDE
SMILES [H]Cl.[C@@H]1(C2=CC=CC=C2)CNCC1

Computational Chemistry Data

TPSA 12.03
LogP 2.1853
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-3-Phenylpyrrolidine hydrochloride

CAS No. 851000-46-9

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